Clinical analysis of therapy with antithyroid drugs connected with L-T_4 for graves disease

Objection: To explore the connect ATD with L-T4 therapy results for Graves disease company significant thyroid and (or ) thyrotoxic ophthalmopathy. Methods: Selected that first treatment Graves disease company significant throid gland and thyrotoxic ophthalmopathy 100 cases, randomly divided into two groups, A groups were given ATD and L-T4, B groups were only given ATD. Results: TRAb converted negative rate of A groups from 80.1% down to 16.6% significantly higher than that of B groups from 82.4% down to 43.5%. But recurrence rate of A groups significantly low that of B groups. 7 cases recrudesced (14.6%), 41 cases cured (85.4%) in the treat group; 16 cases recrudesced (34.8%), 30 cases cured (65.2%) in the control group, and there is significant difference between them. Conclusions: Graves disease company significant thyroid gland and (or) thyrotoxic ophthalmopathy, connect ATD with L-T4 can significantly clinical effective.