[A comparative study of the cryoprotective properties of dimethylacetamide and dimethyl sulfoxide in preserving thrombocytes at moderately low temperatures].
作者
Azovskaia Sa,Iu S Sukhanov,Zhukovskaia Nl,Konoplina La
出处
期刊:PubMed [National Institutes of Health] 日期:1989-12-01卷期号:34 (12): 18-21
Comparative characteristics of cryoprotective properties of dimethylacetamide and dimethyl sulfoxide (DMAC and DMSO, respectively), used for freezing and storage of platelets at -80 degrees C, have been presented. It is shown that with the studied final concentrations of the cryoprotectors (5% of DMSO, 2.5% of DMAC), solutions containing DMSO display higher cryoprotective properties. Positive effect of autoplasma in the mixture with the platelet-protecting solution has been manifest in the maintaining of the functional properties of platelets after defrosting.