Objective: To observe the changes of 6 bands frequency-fluctuation characteristics of EEG under vigilance task. Methods: The experiments were carried out for 80 minutes by computer simulated monitoring task. Results: (1) high band β wave exercise was the main EEG exrcise during vigilance task, low band wave exercise under 13 Hz was waken or inhibited. (2) The dominant band frequency-fluctuation decreased significantly after vigilance task, which showed the brain fatigue increased. (3) P4 area was the area with the most intensive during vigilance task and the highest degree of fatigue after the task, O1, O2, P3, and FP1 area also showed tired. Dominant θ band (5-7HZ) at O1, O2, P3 and P4 areas occurred when eye-opened after the 80 minutes task. O1, O2, P3, P4 were the main areas of information processing in visual vigilance, and FP1 were related with the activity of eyes. Conclusion: The brain information processing in visual vigilance correlated with the changes of band frequency fluctuation characteristics. This method may be helpful in the study of visual vigilance workloads.