After inoculated sarcocarcinoma S180 into the armpit,14 kinds of polysaccharides(100mg/kg) were fed into stomach of the mice every day.The inhibition rate,weight,thymus and splen index,the number of red cells and white cells were investigated.The results showed that the polysaccharides,isolated from Codonopsis Pilosula(Fr.) Nannf.Polysaccharide,Adenophora tetraphylla(Thunb.) Fisch Polysaccharide,Broussonetia papyrifera(Linn.)Vent.Polysaccharide,Rosa roxburghii Tratt Polysaccharide,Balanophora spicata Hayata.Polysaccharide,Rosa laevigata Michx.Polysaccharide,Epimedium pubescens Maxim Polysaccharide,Campanumoea javanica B1.var.japonica Makino Polysaccharide,Curculigo orchioides Gaertn Polysaccharide,Gynostemma pentaphyllum(Thunb.) Mikino.Polysaccharide,and the Disporopsis pernyi(Hua) Diels.Polysaccharide demonstrated inhibitory effects on S180 tumor.