The Strong program of scientific knowledge sociology established by Edinburgh School questioned rationalism and created the theory of scientific knowledge sociology.TheStrong programmehas rich theoretical background,which is mainly influenced by Wittgenstein’s Post-philosophy,Sociology of Knowledge and Constructivism.Firstly,Wittgenstein’s analysis about language and thought provided philosophy theoretical basis to construct the strong programme.Secondly,the distribution patterns and their influential factors of belief paid attention by Sociology of Knowledge are the main problems thatStrong programmeshould answer and solve,and the impliedsocial determinismalso greatly inspired the Edinburgh School.At last,the infiltration of constructivism from philosophy to society provided a direct theoretical source for the Edinburgh School to constructstrong programof sociology of scientific knowledge.