医学
铜绿假单胞菌
鲍曼不动杆菌
抗菌剂
不动杆菌
抗生素
细菌
烧伤
内科学
微生物学
外科
伤口愈合
生物
遗传学
作者
İlker Devrim,Ahu Kara,Mine Düzgöl,Aytaç Karkıner,Nuri Bayram,Günyüz Temır,Aydın Şencan,Yelda Sorguç,Gamze Gülfidan,Münevver Hoşgör
出处
期刊:Burns
[Elsevier]
日期:2017-02-01
卷期号:43 (1): 144-148
被引量:31
标识
DOI:10.1016/j.burns.2016.07.030
摘要
Infections are the leading cause of morbidity and mortality in patients with burns in burn units. Bloodstream infections (BSIs) in patients with burns may result from burn wound infection, use of invasive devices such as central venous catheters, and translocation of the gastrointestinal flora. In this study, we investigated the distribution and antimicrobial drug resistance of causative pathogens in children with burns and the durational changes of microorganisms in the distribution of BSIs in children. This study was conducted at the Pediatric Burn Unit (PBU) of Dr. Behçet Uz Children Research and Training Hospital during the period of November 2008–April 2015. The study subjects were all the patients admitted to the PBU, in whom microorganisms were isolated at least from one of the cultures, including blood and catheter cultures. Gram-positive bacteria were the most common causative agents of BSI in patients with burns (66.4%), followed by gram-negative bacteria (22.1%) and fungi (11.5%). The median duration of development of BSIs caused by gram-positive bacteria from the time of burn was 5 days (ranging from 2 to 54 days of burn), which was significantly shorter than that of BSIs caused by gram-negative bacteria (12 days) and fungal pathogens (13 days). The etiologic agents of BSIs in children may differ from those in adults. Gram-negative drug-resistant bacteria such as multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii were important agents of BSI in patients with burns, especially in the long term; however, gram-positive bacteria should also be considered while deciding the antimicrobial therapy, especially in the early periods of burn.
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