生物
抑制性突触后电位
小胶质细胞
神经科学
兴奋性突触后电位
混乱
生物神经网络
突触
感受野
心理学
免疫学
炎症
精神分析
作者
Emilia Favuzzi,Shuhan Huang,Giuseppe-Antonio Saldi,Loïc Binan,Leena A. Ibrahim,Marian Fernández-Otero,Yuqing Cao,Ayman Zeine,Adwoa Sefah,Karen Zheng,Qingru Xu,Elizaveta Khlestova,Samouil L. Farhi,Richard Bonneau,Sandeep Robert Datta,Beth Stevens,Gord Fishell
出处
期刊:Cell
[Cell Press]
日期:2021-10-01
卷期号:184 (22): 5686-5686
被引量:72
标识
DOI:10.1016/j.cell.2021.10.009
摘要
(Cell 184, 4048–4063.e1–e32; July 22, 2021) It has come to our attention that, in the originally published version of our article examining how GABA-receptive microglia selectively regulate the development of inhibitory synapses in the mouse, Figure 1B had an accidental duplication of the data from the P4 samples instead of P8 (as indicated). The duplication occurred on a preliminary graph that initially contained data from all ages but was later split. We have now updated Figure 1B to reflect the correct data from the P8 experiments. The revised data do not change the conclusions or the interpretations of this experiment or the paper as a whole. This error has now been corrected in the article online, and the authors apologize for any confusion it may have caused.Figure 1BMicroglia depletion during cortical development alters inhibitory and excitatory synapse connectivity (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) GABA-receptive microglia selectively sculpt developing inhibitory circuitsFavuzzi et al.CellJuly 6, 2021In BriefGABA-receptive microglia selectively prune inhibitory synapses in development and disruption of this microglial response leads to behavioral abnormalities highlighting a critical function of selective communication between microglia and neuronal cell types. Full-Text PDF
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