Objective In order to improve nursing strategy for patients with lung cancer who underwent radiotherapy,risk factors for radiation pneumonitis were investigated.Methods 50 patients with radiation pneumonitis were studied,the relationship betweent V5,V10,V15,V20,V25,V30,V35,V40,Dmean and radiation pneumonitis were investigated using univariate and multivariate analysis.Results Smoking and chemotherapy were associated with radiation pneumonitis by univariate analysis,dose-volume metrics V5,was significantly associated with radiation pneumonitis.Conclusion Close observation and nursing care is helpful in the treatment of radiation pneumonitis and completion of radiotherapy.