Sorbic acid has been recognized so far as one kind of the best antiseptic agents that can participate in normal metabolism of human body.Sorbic acid is well-known food preservative,but it has little preservative effect in the neutral condition and it also has poor water solubility.Potassium sorbate has good water solubility,but it can not turn into sorbic acid molecular which has preservative effect in the acid condition.The study on advancing sorbic acid and potassium sorbate's effect in antisepsis was summarized.