化学
芳基
功能群
组合化学
分子
接受者
可见光谱
环境友好型
相容性(地球化学)
光化学
有机化学
化学工程
生态学
烷基
物理
光电子学
工程类
生物
凝聚态物理
聚合物
作者
Jie Gao,Zhipeng Ye,Yu-Fei Liu,Xian-Chen He,Jianping Guan,Fang Liu,Kai Chen,Hao-Yue Xiang,Xiao‐Qing Chen
出处
期刊:Organic Letters
[American Chemical Society]
日期:2022-06-21
卷期号:24 (25): 4640-4644
被引量:8
标识
DOI:10.1021/acs.orglett.2c01750
摘要
A photoinduced, photocatalyst-free cyanoalkylation of nitrostyenes was explored, affording a series of cyanoalkylated alkenes in moderate to good yields. Mechanistic studies reveal that an electron donor-acceptor complex formed between O-aryl oximes and DIPEA is presumably involved in this process. The excellent functional group compatibility of this newly designed synthetic protocol allows for cyanoalkylation of structurally varied substrates, which offers an eco-friendly pathway for the assembly of cyanoalkylated alkenes.
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