生物
肠上皮
细胞生物学
上皮
真菌
微生物学
免疫学
作者
Daniel H. Cho,Gloria B. Choi
出处
期刊:Immunity
[Elsevier]
日期:2022-04-01
卷期号:55 (4): 586-588
标识
DOI:10.1016/j.immuni.2022.03.012
摘要
The impact of intestinal fungi on host physiology and their mechanisms of interaction are incompletely understood. In a recent issue of Cell, Leonardi et al. (2022) showed that mucosal fungi induce intestinal Th17 cells to produce IL-22 and IL-17A. IL-22 acts on the gut epithelium to protect barrier integrity, whereas IL-17 acts on IL-17RA+ neurons to enhance sociability.
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