Age at onset of genetic disease and genetic dependent stage: evidence from cases with SCN1A variants

Journal Article Accepted manuscript Age at onset of genetic disease and genetic dependent stage: evidence from cases with SCN1A variants Get access Sheng Luo, Sheng Luo Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China https://orcid.org/0000-0002-7184-1267 Search for other works by this author on: Oxford Academic PubMed Google Scholar Peng-Yu Wang, Peng-Yu Wang Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Wen-Hui Liu, Wen-Hui Liu Department of Neurology, The First Affiliated Hospital & Clinical Neuroscience Institute of Jinan University, Guangzhou 510632, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Xiao Yu Liang, Xiao Yu Liang Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Yu-Jie Gu, Yu-Jie Gu Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Yi-Chen Ye, Yi-Chen Ye Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Peng Zhou, Peng Zhou Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Yong-Hong Yi, Yong-Hong Yi Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Search for other works by this author on: Oxford Academic PubMed Google Scholar Heng Meng, Heng Meng Department of Neurology, The First Affiliated Hospital & Clinical Neuroscience Institute of Jinan University, Guangzhou 510632, China Correspondence may also be addressed to: Prof. Heng Meng, Department of Neurology, the First Affiliated Hospital & Clinical Neuroscience Institute of Jinan University, 613 West Huangpu Ave, Guangzhou 510632, China, E-mail: [email protected] Search for other works by this author on: Oxford Academic PubMed Google Scholar Wei-Ping Liao for the China Epilepsy Gene 1.0 Project Wei-Ping Liao Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou 510260, China Correspondence to: Prof. Wei-Ping Liao, Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, the Second Affiliated Hospital, Guangzhou Medical University, Chang-gang-dong Road 250, Guangzhou 510260, China, E-mail: [email protected] https://orcid.org/0000-0001-9929-9185 Search for other works by this author on: Oxford Academic PubMed Google Scholar Brain, awaf064, https://doi.org/10.1093/brain/awaf064 Published: 19 February 2025 Article history Received: 17 December 2024 Accepted: 06 February 2025 Published: 19 February 2025