Emerging self-powered piezoelectric based nanobiomaterials as a platform for accelerated wound healing: recent advances and future perspectives

AbstractSpontaneous generation of native endogenous electric fields (EFs) after wounding is the hallmark of enhanced wound healing (WH). Focus has been given toward creation of smart technologies that provide an external EF. Piezoelectric based dressings when applied to wound sites can conveniently generate EF in response to body’s natural movement and promote WH. In this perspective, piezoelectric nanobiomaterials are gaining significant attention due to their high surface energy and complex cell-material interactions. This review discusses role of EF in WH simultaneously exploring their development and use for skin regeneration. Important properties of these materials and future directions are also discussed.Keywords: Wound healingpiezoelectricitynanobiomaterialselectrical stimulation AcknowledgmentsAuthors are thankful to School of Applied Sciences, KIIT Deemed to be University. S. Pattnaik would like to thank the Council of Scientific & Industrial Research (CSIR), Government of India, for providing a junior research fellowship.Conflict of interestThe authors declare no conflict of interest.