化学
重氮
琥珀酸
四氢呋喃
曙红Y
光化学
琥珀酸盐
组合化学
催化作用
光催化
有机化学
溶剂
作者
Hai-Bing Ye,Xu-Yu Zhou,Lei Li,Xiang‐Kui He,Jun Xuan
出处
期刊:Organic Letters
[American Chemical Society]
日期:2022-08-10
卷期号:24 (32): 6018-6023
被引量:28
标识
DOI:10.1021/acs.orglett.2c02313
摘要
We disclosed herein a straightforward photochemical method for the construction of phenanthridines containing a synthetically useful succinate unit. The reaction occurred under visible-light irradiation with cheap eosin Y Na as photoredox catalyst and a diazo compound as the succinate precursor. Under the optimal reaction conditions, a wide range of phenanthridines were obtained in moderate to good yields. Note that the succinate units in the final heterocycles could be easily transformed into many valuable structures, such as γ-butyrolactone, dihydrofuran-2(3H)-one, and tetrahydrofuran. Mechanistic experiments were performed to support the proposed mechanism.
科研通智能强力驱动
Strongly Powered by AbleSci AI