Skin Glycation Damage Therapy Zn-based nanoparticles co-loaded Theasinensin A and L-carnosine synergistically block HMGB1/RAGE and AGEs/RAGE signaling, attenuating glycation-driven skin inflammation and aging. This multi-target nanotherapy offers a potent approach against glycation-induced skin damage. More details can be found in article 2500664 by Tingting Lin, Jing Jin, Caibin Zhu, Huijuan Liu, and co-workers.