Anti-MRSA Activity of Secondary Metabolites Originated from Endophytic Streptomyces sp.

Pathogens resistant to antibiotics are on the rise, and especially among them, methicillin-resistant Staphylococcus aureus (MRSA), is a global issue as it causes additional infections and is difficult to treat. In addition, the value of research related to the development of new drugs showing the effectiveness of antibiotic against MRSA is so high that the World Health Organization (WHO) included MRSA treatments in the list of antibiotics requiring new drugs. The Streptomyces genus is a genus of strains with high research value and many reports have been made on the production of antibiotics, including Streptomyces coelicolor. In this paper, here we firstly summarize the extracts and isolated compounds from endophytic Streptomyces strains that show anti-MRSA activity and compare these with other antibiotics.