NaHMDS/B(C 6 F 5 ) 3 -promoted diastereoselective Friedel–Crafts alkylation of indoles/pyrroles with N-tert -butanesulfinylimines: towards the asymmetric synthesis of bisindole alkaloid Calcicamide B

This study proposed an innovative and pragmatic approach to the asymmetric Friedel–Crafts reaction by employing indoles/pyrroles and chiral N-tert -butanesulfinylimines promoted by NaHMDS/B(C 6 F 5 ) 3 .