We present a novel organometal halide perovskite nanoparticle (OHP-NP) based artificial synapse, designed to mimic biological peripheral nervous systems more effectively. Our artificial synapse exhibits extraordinary sensitivity, operating at ultralow voltages as low as 100 mV, comparable to biological synapses. When stimulated by such low-voltage pulses, the device replicates essential working principles of biological synapses, including excitatory postsynaptic current, paired-pulse facilitation, spike-rate-dependent plasticity, and spike-timing-dependent plasticity. Remarkably, the device's sensitivity allows it to be further stimulated by even lower external pulses, as low as 10 mV, resulting in an ultralow energy consumption of merely 5 fJ per synaptic event (SE). This energy consumption is comparable to that of biological synapses (1 -10 fJ/SE). These results signify a significant advancement towards developing ultrasensitive neuromorphic electronics and artificial nerves that seamlessly interface with their biological counterparts. Our OHP-NP-based artificial synapse holds promise for future applications in neuromorphic computing and biohybrid systems, paving the way for cutting-edge technologies with enhanced sensitivity and energy efficiency.