DNA糖基化酶
DNA损伤
基底切除修复术
DNA修复
氧化应激
化学
突变体
DNA
穆提
突变
生物化学
活性氧
重组DNA
生物
氧化磷酸化
细胞生物学
尿嘧啶DNA糖基化酶
分子生物学
过氧化氢
作者
Doukun Lu,Menghan Zhang,Menghui Liu,Abdul Raheem,Gang Zhao,Yingjie Fu,Xi Chen,Aizhen Guo,Jianguo Chen
标识
DOI:10.1096/fj.202502488rr
摘要
), indicating impaired oxidative DNA repair. Although all three strains similarly induced reactive oxygen species (ROS) production in bovine macrophage (BoMac) cells, the T9.376 mutant exhibited compromised survival under oxidative stress conditions. In conclusion, this study highlights the importance of MbovP486 for M. bovis survival under DNA-damaging conditions during host colonization.
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