Contribution of Interleukin-1 Receptor-Associated Kinase 1 Gene Polymorphism to Systemic Lupus Erythematosus in Chinese Patients

The findings suggest that polymorphisms in IRAK1 are associated with a reduced risk of SLE within a Chinese demographic. These genetic variations may serve as potential biomarkers for assessing SLE risk and offer novel perspectives on the molecular mechanisms that underpin the disease.