Bidirectional two-sample mendelian randomization analysis identifies a causal relationship between major depressive disorder and allergic diseases.

This MR study suggested a nominally significant causal relationship between MDD and increased risk of AR, and a specific condition-based causal relationship between MDD and AAS. In the future, these results need to be validated further. (PsycInfo Database Record (c) 2025 APA, all rights reserved).