社会孤立
心理学
认知
睡眠障碍
调解
痴呆
认知技能
分离(微生物学)
临床心理学
睡眠剥夺对认知功能的影响
认知功能衰退
扰动(地质)
精神科
发展心理学
医学
内科学
疾病
古生物学
法学
微生物学
生物
政治学
作者
Xiang Qi,Yaolin Pei,Susan Kohl Malone,Bei Wu
出处
期刊:The Journals of Gerontology
[Oxford University Press]
日期:2023-01-06
卷期号:78 (10): 1826-1833
被引量:11
标识
DOI:10.1093/gerona/glad004
摘要
Abstract Background Social isolation is prevalent and associated with dementia, yet the directionality and mechanisms are less understood. This study examined the association between social isolation and cognitive functioning and explored the mediating role of sleep disturbance on the social isolation–cognition relationship. Methods Data from 5 753 dementia-free Americans aged ≥50 of 2006 (T1), 2010 (T2), and 2014 (T3) waves of the Health and Retirement Study. Social isolation was measured by the Steptoe Social Isolation Index. Cognitive functioning was measured by the Telephone Interview of Cognitive Status. Sleep disturbance was measured with the modified Jenkins Sleep Scale. We used cross-lagged panel models to determine the associations between social isolation, sleep disturbance, and cognitive functioning. Results Social isolation is significantly associated with subsequent cognitive functioning (T1 to T2: β = −0.055, standard error [SE] = 0.014, p < .001; T2 to T3: β = −0.044, SE = 0.016, p < .001). Lower cognitive functioning is significantly associated with greater subsequent social isolation (T1 to T2: β = −0.101, SE = 0.020, p < .001; T2 to T3: β = −0.058, SE = .011, p < .001). Sleep disturbance at T2 partially mediated the effect of social isolation (T1) on cognitive functioning (T3), accounting for 6.2% of the total effect (β = −0.003, SE = 0.001, p < .01). Conclusions Social isolation may deteriorate cognitive functioning and vice versa. The association between social isolation and cognition is partially explained by sleep disturbance.
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