肥大性骨关节病
发病机制
脊柱骨关节病
医学
内科学
内分泌学
皮肤病科
病理
生物信息学
生物
作者
Zhenlin Zhang,Zhen Zeng
出处
期刊:Chinese Journal of Endocrinology and Metabolism
日期:2016-02-25
卷期号:32 (2): 89-92
标识
DOI:10.3760/cma.j.issn.1000-6699.2016.02.001
摘要
Primary hypertrophic osteoarthropathy(PHO) is a rare inherited osteopetrosis characterized by digital clubbing, pachyderma and periostosis. In the last decade, huge break through in genetic detection technology has facilitated the discovery of the molecular cause of PHO. This article will centre on the advance in pathogenesis, diagnosis, and management of PHO, and provide new ideas for further research. (Chin J Endocrinol Metab, 2016, 32: 89-92)
Key words:
Primary hypertrophic osteoarthropathy; Prostaglandin E2; Pathogenesis; Gonadal hormones
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