Evaluation of Electrospun Poly (Vinyl Alcohol) (PVA)/Gelatin Nanofiber Membrane and Biocompatibility

PVA and gelatin mixed in various volume ratios (100:0, 90:20, 80:20, 70:30, 60:40, 50:50, to 0:100). The effects of the volume ratio on the spinnability of PVA/gelatin solutions were evaluated. The effect on the electrospun nanofiber of PVA/gelatin was examined by IR spectroscopy. Experimental results have demonstrated that solutions of PVA/gelatin in a volume ratio of 80/20 had good spinnability. As the electric field increased, the numbers of beads and droplet decreased. IR spectra demonstrated strong intermolecular hydrogen bonds between the molecules of gelatin and PVA. In this investigation, the best electric field for electrospinning was 0.68 kV/cm. The critical electric field for electrospinning is 0.5 kV/cm.