嘧啶
区域选择性
环加成
化学
嘌呤
叠氮化物
点击化学
烷基化
组合化学
三唑
立体化学
催化作用
有机化学
酶
作者
Romain Lucas,Pierre‐Henri Elchinger,Pierre-Antoine Faugeras,Rachida Zerrouki
标识
DOI：10.1080/15257771003708579
摘要
Abstract This article describes a synthetic route to generate two purine-pyrimidine and pyrimidine heterodinucleosides. Both microwave activated regioselective alkylation using hydride and copper-catalyzed-azide-alkyne-cycloaddition (CuAAC) were used in order to perform the synthesis. Keywords: Oligonucleotides analoguesclick chemistrymicrowave-activated synthesis
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