Effect of Bright Light in the Hospital Nursery on the Incidence of Retinopathy of Prematurity

早产儿视网膜病变 医学 入射(几何) 视网膜病变 儿科 出生体重 低出生体重 新生儿重症监护室 眼科 胎龄 怀孕 内分泌学 生物 光学 物理 糖尿病 遗传学
作者
Penny Glass,Gordon B. Avery,K. N. Siva Subramanian,Marshall P. Keys,Anita Miller Sostek,David S. Friendly
出处
期刊:The New England Journal of Medicine [New England Journal of Medicine]
卷期号:313 (7): 401-404 被引量:215
标识
DOI:10.1056/nejm198508153130701
摘要

The preterm infant is subjected to prolonged exposure to ambient nursery illumination at levels that have been found to produce retinal damage in animals. We prospectively investigated the effect of exposure to light in two intensive care nurseries by comparing the incidence of retinopathy of prematurity among 74 infants from the standard bright nursery environment (median light level, 60 foot-candles [ftc]) with the incidence among 154 infants of similar birth weight for whom the light levels were reduced (median, 25 ftc). There was a higher incidence of retinopathy of prematurity in the group of infants who had been exposed to the brighter nursery lights, particularly in those with birth weights below 1000 g (86 percent vs. 54 per cent, P less than 0.01 by chi-square test). We conclude that the high level of ambient illumination commonly found in the hospital nursery may be one factor contributing to retinopathy of prematurity and that safety standards with regard to current lighting practices should be reassessed.
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