Objectives: This study aimed to investigate the predictive ability of perfectionism and test anxiety in academic burnout among Yarmouk University students. Methodology: The descriptive-predictive approach was used to reveal the predictive ability of perfectionism and test anxiety in academic burnout among Yarmouk University students, as it was appropriate to the nature and objectives of the study. Results: The results showed that the predictive model of the predictor variables for the predicted variable (academic burnout) had a combined effect of the independent variables explaining 59.50% of the total explained variance of the predictive model. The independent variable (test anxiety) contributed the most in the first place, with a relative effect explaining 52.00% of the total explained variance. The independent variable (organization) contributed in the second place, explaining 4.00%. The independent variable (personal standards) contributed in the third place, explaining 2.20%. The independent variable (anxiety about mistakes and doubt about performance) contributed in the fourth place, explaining 0.90%. The independent variable (parental expectations and parental criticism) contributed in the fifth place, explaining 0.30% of the total explained variance of the predictive model. Conclusion: The study concluded that test anxiety was the strongest predictor of academic burnout among university students, followed by organization, personal standards, anxiety about mistakes, and parental expectations or criticism. In light of these results, the study recommends conducting interventions to reduce test anxiety and address maladaptive perfectionism to prevent academic burnout. Keywords: Perfectionism, Test Anxiety, Academic Burnout, University Students.