化学
废止
磺酰
催化作用
铜
药物化学
组合化学
立体化学
有机化学
烷基
作者
Biao Yao,Tao Miao,Pinhua Li,Lei Wang
出处
期刊:Organic Letters
[American Chemical Society]
日期:2018-12-21
卷期号:21 (1): 124-128
被引量:20
标识
DOI:10.1021/acs.orglett.8b03564
摘要
A novel and efficient strategy for the direct synthesis of benzo[ f]indazoles via copper-catalyzed cascade reaction of sulfonyl hydrazides with 1,3-enynes under mild conditions has been developed. This method achieves the formation of two C-N bonds and one C-C bond in one pot, providing a series of benzo[ f]indazoles in moderate to good yields with good functional group tolerance and remarkable regioselectivity.
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