免疫系统
抗原
癌症研究
佐剂
医学
免疫学
热休克蛋白90
免疫疗法
T细胞
抗原呈递
生物
热休克蛋白
生物化学
基因
作者
Alex M. Jaeger,Lauren Stopfer,Sunmin Lee,Giorgio Gaglia,Demi Sandel,Sandro Santagata,Nancy U. Lin,Jane B. Trepel,Forest M. White,Tyler Jacks,Susan Lindquist,Luke Whitesell
标识
DOI：10.1158/1078-0432.ccr-19-0596
摘要
These highly translatable observations support reconsideration of the most effective strategy for targeting HSP90 to treat cancers and suggest a practical approach to repurposing current orally bioavailable HSP90 inhibitors as a new immunotherapeutic strategy.See related commentary by Srivastava and Callahan, p. 6277.
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(2025-6-4)
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