Clinical observation in Kanglaite Injection on serum alpha-fetoprotein and physical conditions of advanced hepatocellular carcinoma patients

Objective To observe the inhibition of Kanglaite Injection on serum alpha-fetoprotein (AFP) and the influence on physical condition of advanced hepatocellular carcinoma patients. Methods The 62 patients with advanced hepatocellular carcinoma were randomly divided into two groups. The control group was given liver-protected drugs and biological reaction regulator with the symptomatic treatment, while the treatment group was given 100 mL Kanglaite Injection via iv infusion. Results After treatment the benefit ratio of AFP in the control group was 54.84% and that in the treatment group was 87.10%. The benefit ratios of Karnofsky (KPS) score in the two groups were 61.29% and 83.87% both significant difference (P0.05). Conclusion Kanglaite Injection could obviously decrease the AFP level in peripheral blood of advanced hepatocellular carcinoma patients and improve the physical state and life quality of the advanced hepatocellular carcinoma patients.