Chemical constituents from roots and rhizomes of Physochlaina infundibularis

Objective To investigate the chemical constituents from the dried roots and rhizomes of Physochlaina infundibularis.Methods Repeated chromatography with silica gel,macroporous resin,MCI,and Sephadex LH-20 columns was used to isolate the chemical constituents and their structures were elucidated based on physicochemical properties and spectral data.Results Seventeen compounds were isolated and identified as hyoscyamine(1),scopolamine(2),anisodamine(3),scopoletin(4),scopolin(5),umbelliferone(6),6,7-dimethoxycoumarin(7),3-methoxyquercetin(8),isoquercitin(9),kaempferol-7-O-β-D-glucoside(10),syringarenol(11),protocatechuic acid(12),methyl 4-hydroxybenzoate(13),2-hydroxybenzoic acid(14),tropic acid(15),4hydroxybenzoic acid(16),and palmitic acid(17).Conclusion Compounds 7—17 are firstly obtained from the plants in Physochlaina G.Don,and compound 5 is firstly obtained from P.infundibularis.