Social and economic benefit were increased with the rapid development of technology of agricultural genetically modified organism,meanwhile,improving the risk communication mechanism of agricultural genetically modified organism which suitable for public participation was particularly important. Based on the analysis of the connotation of risk communication of agricultural genetically modified organism, the mode and effect of risk communication of genetically modified organism in foreign countries were introduced and the objective demands for risk communication and interaction mechanism were studied in the paper from different angles, including researcher,governor,public and so on. The suggestions for perfect long-term mechanism of risk communication of agricultural genetically modified organism were proposed to promote the healthy and sustainable development of the industry of agricultural genetically modified organism in China.