Observations on betel-nut use, habituation, addiction and carcinogenesis in Papua New Guineans.

The method of use of betel nut in Papua New Guinea is described and the pharmacology and effects of betel nut reviewed. Both the social importance of betel-nut chewing in Papua New Guinea and its deleterious effect on health are emphasized. There is a need for more active and culturally appropriate health education programs to help prevent the negative effects of betel-nut chewing.