Objective To explore the diagnostic value of multi-slice computed tomography(MSCT)in the primary epiploic appendagitis(PEA).Materials and Methods A retrospective analysis of 5 patients with PEA proved by surgical operation was performed and 5 patients were evaluated with pelvic and lower abdominal MSCT.The CT findings of PEA including location,echogenicity,size,margin and vascularity were observed.Results All cases with PEA occurred around the colons.Among these cases,1cases were found around cecum,1 case around ascending colon,3 around sigmoid colon respectively.The CT features of PEA were characteristic,which were a round or oval pericolonic fatty lesion with a hyperdensity rim(ring sign) and adjacent fat stranding with an absence of other causes of inflammation.Conclusion PEA has characteristic MSCT appearances,MSCT MPR is of great value in the diagnosis of PEA.