Vitreoretinal surgery has entered the era of minimally invasive surgery after decades of development. The development of equipment and technology, represented by 25G and 23G vitrectomy, makes the incision smaller and sutureless. However, the "micro-incision" surgery is not the same as "minimally invasive surgery". The key of "minimally invasive surgery" is that the surgeons should have a strong "minimally invasive" consciousness, always follow the "minimally invasive principle", produces minimal trauma to obtain the best outcome. The ideal minimally invasive vitrectomy should be the perfect combination of "minimally invasive technique" and "minimally invasive devices and equipment" under the guidance of "minimally invasive consciousness".