Treatment of Diabetes with Insulin

This chapter contains sections titled: How is insulin that is used therapeutically produced? How do commercially available insulin preparations differ from each other? What are insulin analogues? Why are there so many different insulin preparations? What does the speed of insulin absorption after a subcutaneous injection depend on? What does insulin bioavailability depend on? Is the injection of insulin with a pen preferable? What are the side effects of insulin treatment? How many types of insulin therapy exist and what are they? How are the types of insulin therapy that imitate the physiologic secretion of insulin planned? What are the advantages and disadvantages of an intensified insulin regimen? Are there conditions for the application of basal-bolus insulin regimens? How is the substitution of basal insulin secretion done? Which is the most preferable basal insulin? How is the substitution of ‘prandial’ insulin done? What is the most preferable ‘prandial’ insulin? When is basal insulin administered and how is its dose determined? How are doses of ‘prandial’ insulin determined? What are the indications for insulin administration in Type 2 DM? What insulin therapy regimens are used in Type 2 DM? What is the regimen of choice for the initiation of insulin therapy in individuals with Type 2 DM? What constitutes the schemes of basal insulin-pills? How do the schemes with premixed insulin preparations work? Are intensified regimens of basal-bolus insulin administered in Type 2 DM? Case Study 1 Case Study 2 Case Study 3 What should be done with regard to the glycaemic control of this patient? Case Study 4 Case Study 5 Further reading