鸦片剂
（+）-纳洛酮
受体
药理学
敌手
医学
神经组织
中枢神经系统
阿片受体
化学
神经科学
吗啡
内科学
内分泌学
生物
作者
Candace B. Pert,Solomon H. Snyder
出处
期刊：Science
[American Association for the Advancement of Science]
日期：1973-03-09
卷期号：179 (4077): 1011-1014
被引量：2378
标识
DOI：10.1126/science.179.4077.1011
摘要
Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig intestine. Competition for the opiate receptor by various opiates and their antagonists closely parallels their pharmacological potency. The opiate receptor is confined to nervous tissue.
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