Coronavirus disease 19 (Covid-19) and non-steroidal anti-inflammatory drugs (NSAID)

We have read with interest the report by Monti et al 1 concerning the clinical course of coronavirus disease (Covid-19) in patients with chronic inflammatory arthritis. However, we could not find data about the use of non-steroidal anti-inflammatory drugs (NSAID) among their patients. Whether concomitant NSAID treatment may be harmful or safe in patients with Covid-19 is unknown. However, anti-inflammatory therapies might prevent fatal cytokine storm of Covid-19. Ibuprofen, a commonly prescribed NSAID, was found to reduce interleukin-6 (IL-6) in human tissues,2 and in sputum. …