A comparative study of 99Tcm-diethylene triaminepentaacetic acid and 99Tcm-octreotide orbital scan in thyroid associated ophthalmopathy

Objective Through a comparative study of 99Tcm-diethylenetriaminepentaacetic acid (99Tcm-DTPA) and 99Tcm-octreotide (99Tcm-OCT) SPECT orbital scan, evaluated the clinic significance of two imaging of estimation activity in thyroid associated ophthalmopathy (TAO). Methods Aeording to the elinnic activity score (CAS), 26 TAO patients were divided into two groups: active group (CAS ≥3) and inactive group (CAS 0.05). There is a statistically significant correlation was found between CAS and the uptake ratios(99Tcm-DTPA: r=0.835, P<0.001; 99Tcm-OCT: r=0.912, P<0.001). Conclusions There is a good uniformity between 99Tcm-DTPA and 99Tcm-OCT orbital scan; 99Tcm-DTPA is a feasible and maybe a new promising estimation method of activity in the patients with TAO. Key words: Technetium Tc 99m pentetate ;  Technetium Tc 99m octreotide ;  Tomography,emission-computed,single-photon ;  Graves ophthalmopathy ;  Orbit ;