It is still a technical challenge to obtain a 1.55 µm passively Q -switched Er3+/Yb3+ pulse laser with high energy and high repetition frequency, especially when it is end-pumped by a continuous-wave 0.98 µm diode laser. Benefitting from its long fluorescence lifetime of the 4I13/2 upper laser level and high thermal conductivity, Er:Yb:Lu2Si2O7 crystal may be an excellent gain medium for realizing a high energy and high repetition frequency 1.55 µm pulse laser. At a continuous-wave absorbed pump power of 6.1 W, a 1537 nm pulse laser with energy of 45.5 µJ, repetition frequency of 1.32 kHz, and duration of 25 ns was first, to the best of our knowledge, realized in an Er:Yb:Lu2Si2O7 crystal.