内质网
荧光
氧化应激
糖尿病
化学
医学
生物物理学
内科学
内分泌学
生物化学
生物
光学
物理
作者
Weiyao Zhang,Wenhui Song,Weiying Lin
摘要
Diabetes is closely related to the presence of excess HClO induced by endoplasmic reticulum stress. Thus, a novel two-photon fluorescent probe was designed and synthesized for the detection of HClO in the endoplasmic reticulum. Significantly, it has been verified that high glucose can indeed induce oxidative stress of the endoplasmic reticulum and produce excessive HClO. Moreover, the probe has also been successfully used in tissue imaging of diabetic mice.
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