The remarkable porosity, structural tunability, and big surface area of metal-organic frameworks (MOFs) have made them very adaptable materials for gas separation and storage. This review delves into the latest developments in the gas storage application of MOFs, namely in the areas of gas separation technologies and the capture of hydrogen, methane, and carbon dioxide. For selective gas adsorption and desorption, MOFs are ideal due to their design flexibility, which permits exact control over pore size, shape, and functionality. Our focus is on recent advancements in metal-organic framework (MOF) synthesis, functionalization, and hybrid structures. These developments have been essential in improving separation efficiency and gas storage capacities. Problems with stability, scalability, and cost are also discussed, as are possible future approaches to using MOFs in gas separation and storage systems in industry. Given their adaptability, MOFs are promising building blocks for renewable energy sources and technologies that lessen our impact on the environment.