Prophylactic antibiotics for immunosuppressed individuals with anterior nasal packing: A propensity score matched analysis

Results from this large database study of immunosuppressed individuals with ANP after epistaxis demonstrate similar rates of CSIs between cohorts who did and did not receive prophylactic antibiotics. Although adverse drug event rates were also similar, they exceeded CSI rates. Clinicians should consider these findings, the rates of adverse drug reactions, and concern for antibiotic stewardship when evaluating the need for prophylactic antibiotics in this immunosuppressed population.