Development of Flexible Electronic Biosensors for Healthcare Engineering

Wearable biosensors have attracted considerable attention because of their potential use in real-time monitoring and personalized disease diagnosis. The good deformability and stretchability of flexible electronics enable the elimination of expensive and bulky detection instruments, combination of diagnosis and treatment strategies, modification of traditional clinical practice involving invasive detection methods, and creation of a new platform for personalized wearable medical devices. Using a combination of flexible devices, new sensing mechanisms, and structural design methodologies, continuous physiological health checks can be realized under the premise of noninvasiveness; moreover, physiological information obtained from the human body can be transformed into intuitive data and medical staff can realize predictive and objective disease diagnosis. Most of the present reviews have focused on introducing the material composition of flexible sensors. In this study, we initially focus on electronic sensing and subsequently focus on the electronic technology itself. Then, the latest developments associated with flexible and wearable sensing devices are discussed and the sensing of continuous monitoring is summarized. The mechanism, system structure, typical applications, current challenges, and possible future development associated with the usage of biosensors are presented.