Emergence of ST23-K1 blaKPC-3-positive hypervirulent carbapenem-resistant Klebsiella pneumoniae from China: A molecular, biological, and epidemiological study

The present study corroborates the emergence of hypervirulent CR-hvKP in the Zhejiang region, a phenomenon that is presumably attributable to the acquisition of an IncFIB virulence plasmid and a bla_KPC-3 resistance plasmid by the ST23-K1 type K. pneumoniae. Our findings highlight the urgent need to use antibiotics more wisely to limit the emergence of resistance.