Aminium-Radical-Mediated Intermolecular Hydroamination of Nonactivated Olefins

Abstract Aminium radicals are attractive intermediates in synthetic chemistry that readily participate in a series of C–N bond-forming processes. Here, we briefly discuss strategies for generating aminium radicals from various precursors in the context of intermolecular alkene amination, and we highlight recent advances in aminium-radical-mediated hydroaminations of nonactivated olefins to directly approach alkylamines. 1 Introduction 2 Intermolecular Hydroamination of Nonactivated Alkenes with Alkylamines under Photoredox Catalysis 3 Intermolecular Hydroamination of Nonactivated Alkenes with Aliphatic Azides 4 Conclusions