癌症免疫疗法
免疫系统
效应器
免疫疗法
癌症
癌细胞
癌症研究
免疫检查点
医学
免疫学
内科学
作者
Weici Liu,Zheshun Pi,Wenjun Mao
标识
DOI:10.1016/j.trecan.2023.12.001
摘要
Accumulated research corroborates the feasibility of microbial antitumor therapies, enriching the diversity of cancer therapeutics. Recently, Ferrari et al. revealed the role of postbiotics in sensitizing cancer cells to immune checkpoint inhibitors (ICIs) and synergizing immunotherapy. Particularly, phytosphingosine induces upstream MYD88/NF-κB and downstream NLRC5 activation, enhances T cell effector responses, and inhibits tumor growth.
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