Prognostic impact of margin width after R0 Hepatectomy in patients with early solitary hepatocellular carcinoma: A meta-analysis

Review question / Objective: Compared with narrow margin, wide margin can improve the clinical prognosis (RFS, OS) of patients with isolated hepatocellular carcinoma undergoing RO hepatectomy?Condition being studied: R0 was any resection with a minimum 1 mm of negative margin，negative resection margin could really reduce the recurrence rate after liver resection.A number of articles found that a w i d e s u rg i c a l M a rg i n p ro l o n g s t h e prognosis of HCC patients compared to a narrower surgical margin,but still need to INPLASY 1 International Platform of Registered Systematic Review and Meta-analysis Protocols INPLASY PROTOCOL Prognostic impact of margin width after R0 Hepatectomy in patients with early solitary hepatocellular carcinoma: A meta-analysis