Herbal Remedies for Hair Loss: A Review of Efficacy and Safety

Hair loss (HL)is a prevalent condition worldwide, it can affect males and females of different age groups, despite the availability of many conventional treatment options, they may be linked to causing different side effects, leading to a growing interest in natural and herbal remedies (HRs). this review aims to investigate the efficacy and safety of various HRS for HL and examine the current scientific evidence behind them. A literature search was conducted using PubMed, Scopus, and Google Scholar databases to identify relevant studies published up to March 2024. Potential benefits in promoting hair growth (HG) and treating various forms of HL has been suggested by these studies, these remedies were found to be effective in different conditions, including androgenetic alopecia (AGA), telogen effluvium, and alopecia areata (AA), through various mechanisms of action (MOA), including 5α-reductase inhibition, increased microcapillary blood flow, antioxidant and modulation of the HG signaling pathways. However, many of these studies have limitations such as lack of long-term follow-up, small sample sizes and short treatment durations, due to this variation in the quality of evidence, further well-designed randomized trials with larger sample sizes required to confirm efficacy of these HRs.