感觉
伤害
疼痛感
慢性疼痛
医学
伤害感受器
病态的
刺激(心理学)
神经病理性疼痛
感觉系统
转移性疼痛
发病机制
神经科学
物理医学与康复
心理学
麻醉
物理疗法
病理
内科学
受体
心理治疗师
作者
Pradeep Dinakar,Alexandra Stillman
标识
DOI:10.1016/j.spen.2016.10.003
摘要
The pathogenesis of pain sensation includes mechanisms that result in acute or chronic pain. Pain itself is described as an unpleasant sensory and emotional experience beginning with a peripheral stimulus that undergoes a physiological process ultimately resulting in the sensation of pain. Biologists recognize pain to be a common sign of potential tissue damage. Hence, pain sensation is protective in function. However, pathologic states of pain exist secondary to disruption of the nociceptive process both peripherally and centrally or secondary to psychological conditions. It is essential to identify these aberrant states of pain and distinguish them from situations of potential tissue damage. Chronic pain is defined as pain that exceeds 3 or 6 months duration. This article is an overview of the essential neuroanatomy and neurophysiology of normal pain nociception, its clinical implications, and the development of persistent and pathological pain conditions following improperly or poorly treated pain.
科研通智能强力驱动
Strongly Powered by AbleSci AI